Hallo! This is Lauren again, writing our annual summary of lab activities. I guess it’s been a busy year behind the scenes, since I see this is the first blog post since 2023’s annual wrap-up! 2024 has been momentous for me personally since my efforts were focussed on securing a faculty position, aka finally getting myself a ‘real job’. After a competitive application and interview process, I am delighted to have been awarded the post of Associate Professor in Cell Wall Biochemistry at KTH Division of Glycoscience, allowing me to continue in my current department while taking an important career step. The process of applying and interviewing for this job (and similar posts in three other universities…!) has been incredibly draining, and dominated my activities to a significant extent. So I am happy to have had a great team around me whom I could rely on to keep things bubbling away in the lab. The year ended beautifully with warm feelings and celebratory moments: we caught up with friends at the WWSC Winter Workshop, I attended the PhD graduation ceremony at Stockholm City Hall, everyone gathered for a special fika to congratulate me on my Assoc Prof appointment, and then our Division hosted the Departmental Christmas party 🙂

Research
The most significant research news this year was our Nature Communications paper about family 92 carbohydrate binding modules, which you can also read about on the family’s CAZypedia page. This was a hugely important collaborative work from our team with invaluable contributions from Scott and Johan at Chalmers University, and it’s already opened some doors towards additional new collaborations. And, judging by the peer review requests I get now, I am officially “that CBM lady” (I’m okay with it). Towards the end of 2024, Pakinee and I started working on the first manuscripts from her PhD project, which we can hopefully share with you next year!
Students
Pakinee’s PhD is in full swing. She has made tremendous research progress this year, completed a lot of KTH courses and attended two week-long schools with the WWSC Academy. Erik’s Master’s thesis project was tough but taught us a lot about construct design in our engineered enzyme-CBM proteins. His work was within the context of the newly funded Vetenskapsrådet project that began January 2024. Simon joined us after summer to begin a 6-month Erasmus-supported thesis project – another tricky one, testing his protein production skills and giving him a chance to learn carbohydrate analysis. We hosted Niendy, a guest PhD student from Thailand, for three months in Autumn, where she aimed to produce and characterise three CBMs from a bizarre multi-modular GH5 enzyme that shows activity on multiple polysaccharides (CBM-depending, I believe). Niendy’s supervisor Assoc Prof Patthra Pason came for a week-long visit in November, and it was great fun to show her around as well as attending her various seminars in Stockholm. Finally, we were joined in the Autumn term by Christian for a short project, which he will resume in January for his Master’s thesis, looking at fungal cell wall-degrading CAZymes.
Two of the PhD students I co-supervise (both in Francisco Vilaplana’s team at KTH) passed their half-time evaluations this year, I joined the supervisory teams of some more students both at KTH and Chalmers, and we had a few PhD defences as well. It’s really fulfilling to have even a small role in the learning journeys of these brilliant young researchers.

Funding
I was so focussed on applying and interviewing for faculty positions this year, I was kind of too burned out to write a lot of big funding applications myself. However, several collaborative funding proposals were granted with partners at KTH and Chalmers University and right at the end of the year, we got news of an award from Mistra that will support new ventures in the pulp and paper sludge research project, this time collaborating with my good friend Dr Ulrike Schimpf of Stockholm University.
Innovation
Big changes at the spin-off start-up company Glycolink AB! Early in the year, I successfully pitched to private investors and secured funds that allowed us to recruit a new CEO for the company – make sure you follow us on LinkedIn to chart our progress now that Martina Banyay is at the helm! With Martina taking over the role of managing director, I have been able to transition to the much more comfortable position of Chief Scientific Officer (CSO), to which my skills are better suited. Martina is currently seeking investment to build our team and reach commercial status. Towards the end of 2024, we recruited Lovisa Brandt, a former Master’s thesis student from this group who went on to work at EnginZyme for several years, as Senior Research Engineer. She will be driving our biochemical discovery and formulation development work, as well as standardising our protocols and documentation.
Looking ahead
Since 2024 will be my first full year as Associate Professor, I’m both excited and trepidatious about what’s to come. It’s true that myself and my team will have more institutional support and that I’m able to think more long-term about how to build and maintain the group. I also foresee a lot more responsibilities now that I am a full member of the senior faculty. For example, I will have a role in assessing colleagues applying for Docent habilitation, and I’ll be a co-supervisor for at least 8 PhD students in other groups!
When I was offered the position of Assoc Prof at KTH, my Head of Department Istvan gave me some great advice that I will try to keep in mind. In the past few years as Researcher, I have had to work hard to make myself visible, jumping up and down to volunteer for things to flesh out my CV and be eligible for senior faculty roles. Now that I have my position, such responsibilities will naturally flow my way, so I need to learn to be more selective in which tasks I agree to.
I’m hoping to grow the team a bit in the coming years, and to develop new collaborations from a more stable basis at KTH. Please don’t hesitate to get in touch if you see a way for us to work together 🙂














